Prescription guidelines for Anadrol varied a great deal throughout the 1950s – 1980s and was dependent on the medical condition treated, as well as constantly changing FDA guidelines. Medical Anadrol dosages ranged from 2.5mg taken three times per day all the way up to 30mg per day. Eventually in the 1970s, the FDA issued a guideline of 1 – 2mg per kg of bodyweight per day.

Because Anadrol is most commonly manufactured in 50mg tablets, bodybuilding and athletic purposes call for 25 – 50mg per day for a beginner. Intermediate users are known for using a range of 50 – 100mg per day, and although approaching risky limits, advanced users as high as 150mg per day. Generally, however, most users whether beginner, intermediate, or advanced, should seldom require more than 50mg per day due to the sheer potency and strength of Anadrol as an anabolic steroid. This is especially the case when studies have demonstrated that a 100mg Anadrol dosage is indeed more effective than a 50mg Anadrol dosage, but beyond 100mg the results will be no more effective than 100mg itself, and diminishing returns begin to manifest.

An additional point of interest about Anadrol dosages is that many users report a reduction in appetite directly proportional to the dose utilized, and studies have shown that it also increases glucose intolerance and insulin resistance[11], thus making nutrient use by the body less efficient.

Anadrol dosages can and should ideally be split throughout the day so as to ensure stable and steady blood plasma levels of the hormone. Anadrol exhibits a half-life of about 8 to 9 hours in the body, and therefore a schedule involving a morning (AM) dose followed by an afternoon/evening (PM) dose is best.